This new drug is called AndexXa, which refers to its action on Factor Xa, a substance that is inhibited by Xarelto to prevent coagulation. Recently the pharmaceutical company Portola has been working to develop and test an antidote for Xarelto. They have faced lawsuits over deaths from excessive bleeding, and plaintiffs in these cases have stated that the companies have made false claims that Xarelto is more effective than warfarin. So far Xarelto does not have such a life-saving antidote.īayer and Johnson & Johnson, the company that markets Xarelto in the U.S., have come under fire for not adequately warning patients of the risks of the drug. Warfarin has an antidote that reverses the drug’s action to stop excessive bleeding. Patients on blood thinners are at risk for excessive bleeding, which can quickly become fatal. The only problem with drugs like Xarelto is that, unlike warfarin, they do not have antidotes. Drugs like Xarelto were designed to be easier to use than these older drugs, and more effective. Xarelto is a newer blood thinner that prevents blood coagulation in a different way than older stand-by blood thinners like warfarin or heparin. It is used to prevent the formation of blood clots, which can cause heart attacks and strokes that can be fatal. Xarelto is a blood thinner made by Bayer. Patients taking these blood thinners are at risk of excessive bleeding, which can be fatal, and there is currently no approved antidote to reverse the bleeding.

Food and Drug Administration rejected its application for approval or a new antidote for Xarelto and similar blood thinners. Portola Pharmaceuticals recently announced that the U.S.

Xarelto antidote